The revitalization of the Church requires a vocational renewal capable of stimulating participation, communion and mission in Christian communities. However, in order to conceive of such a renewal, we must take stock of the current anthropological challenge, which requires an adequate response in tune with our changing times and the current cultural conditions, marked by migration and the development of digital communication. The proceedings of the Roman Symposium of March 2024 offer a multidisciplinary approach to the anthropological theme, which, in a perspective of openness to universal fraternity, situates the enduring foundations of the Christian vision in relation to the various options circulating on questions of identity, belonging and integration that respects differences. This theological reflection on vocations fills a void and is a valuable resource for the Christian formation of all baptismal vocations, from school to university, in secular or religious settings. It is an indispensable complement to the work of the 2022 Symposium on the priesthood, published in six languages. There is no comparable update on the theme of vocations since the Second Vatican Council.