Agriculture production sustainability and food security have become major global issues in the face of increasing world population and climate change. This book is a comprehensive compilation of current knowledge on integrated approaches and strategies of crop production for agricultural sustainability and food security. It covers a wide range of advanced topics including crop production, nano technological approaches in food and agriculture, waste management, regenerative and climate-resilient agriculture, industrial intervention in agriculture, microbe augmentation for soil restoration, weed management in organic production, post-harvest technology and value addition, and revolutionizing rural agricultural industry. The book provides inclusive coverage of various holistic approaches and strategies aimed at promoting agricultural sustainability and ensuring food security. This includes deliberations on sustainable farming practices, agroecology, biodiversity conservation, climate-smart agriculture, and resource management. The book aims at educating readers, whether they are policymakers, researchers, or students, about the importance of adopting holistic approaches of crop production to address the challenges facing agriculture and food security in today's world. Due to rapidly changing agricultural landscape, complex challenges, knowledge gaps and local contexts, and education and capacity building, this book should serve as a new and complementary resource to address these emerging challenges in agriculture sustainability and food security.