Filling a key need for clinicians working with at-risk Latine adolescents, this book bridges the gap between evidence-based and culturally informed adolescent and family therapy. The authors explore the unique challenges facing Latine youth and families--including immigration- and acculturation-related stressors and minoritization--as well as culturally based sources of resilience. They present Culturally Informed and Flexible Family-Based Treatment for Adolescents (CIFFTA), which combines manualized family and individual interventions. Therapists can select from an extensive list of psychoeducational modules to tailor the intervention to unique client needs. Vivid case examples illustrate high-quality, time- and cost-effective treatment strategies for a range of mental health and substance use problems. The book also provides information about comprehensive CIFFTA training.