A direct sequel to Aliens and Alien 3 Weyland-Yutani, the Colonial Marines, and Bishop's creator all pursue the android for the deadly Xenomorph data contained in his brain. Written by T. R. Napper, author of the acclaimed 36 Streets, whose explosive work explores the artificial intelligence and what it is to be human.

The USCSS Patna has been found.

Although the synthetic Bishop asked to be shut down forever, his creator has other plans. Michael Bishop seeks the Xenomorph knowledge stored in the android's mind, and brings Bishop back to life but for what reason? No longer an employee of the Weyland-Yutani Corporation, Michael tells his creation that he seeks to advance medical research for the benefit of humanity. Yet where does he get the resources needed to advance his work, and with whom do his new allegiances lie?

The USCSS Patna is pursued by Colonial Marines Captain Marcel Apone, commander of the Il Conde and younger brother of Master Sergeant Alexander Apone, one of the casualties of the doomed mission to LV-426. Also on his trail are the 'Dog Catchers', commandos employed by Weyland-Yutani.