Sara and Brian are living an idyllic life with their young son and daughter, Jesse and Kate, when they receive heartbreaking news that leads them to make an unorthodox choice in order to save Kate's life. Anna Fitzgerald, their youngest child, looks to earn medical emancipation from her parents who is relied on to help their leukaemia stricken daughter Kate remain alive. Their decision eventually raises both ethical and moral questions, ultimately revealing surprising truths and challenges everyone s perceptions of love and loyalty, giving new meaning to the definition of healing. Based on the book "My Sister's Keeper" by Jodi Piccoult.