Three girls from Townsville, USA, team-up to fight crime before bedtime.

The city of Townsville celebrates a second season of their half-pint heroines with a birthday bash that almost becomes a real blast thanks to their BFFs - Best Friends Forever. After an attack by Broccoli Aliens, a run in with prissy rival Princess, and a memorable escape from becoming real-life memorabilia, the toughest threesome in town cook up a new Powerpuff Girl to pick up the slack. Little did they know she'd become the kind of baby sister you want to send back. The one thing The Powerpuff Girls can be sure of is that saving the world before bedtime is the most important thing, even when you're put on a curfew.