Managing Bacterial Biofilms

This authoritative volume presents an advanced, interdisciplinary review on the biology, pathogenesis, and control of microbial biofilms across clinical, environmental, food, and industrial settings. The book focuses on the molecular mechanism of quorum sensing and intercellular signaling. It also explores biofilm formation and resistance mechanisms in key bacterial pathogens, alongside chronic biofilm-mediated infections in wounds, sinuses, ocular tissues, and dental plaques. Further, the chapters present device-associated infections and hospital-acquired biofilm complications, with an integrated review of innovative therapeutic options such as phage therapy, enzyme-based disruption, CRISPR-Cas antibiofilm tools, and smart nanomaterials. Beyond clinical implications, the book extends into biofilm dynamics in fresh produce spoilage, power plants, oil and gas industries. Towards the end, the book reviews the recent advancements in diagnostic imaging and AI-driven biofilm management. It is useful for students and researchers of microbiology, biotechnology, food, and environmental sciences.

Key Features:

• Examines biofilms in human health, industrial settings, and energy systems
• Explores cutting-edge biofilm control strategies such as phage therapy, enzyme-based disruption, CRISPR-Cas systems, and nanotechnology-based solutions
• Highlights the growing concern of biofilm contamination on medical implants and hospital surfaces, with practical approaches for prevention and treatment
• Addresses biofilm roles in wastewater treatment, bioremediation, microplastic colonization, and environmental sustainability
• Introduces AI and machine learning for biofilm detection, prediction, and targeted disruption strategies in various environments