In 2002, when all living mammals with a Y chromosome suddenly simultaneously die, Yorick Brown and his pet male monkey Ampersand must figure out why they were the only two males to survive. And while this makes Yorick the most important person in the world, he trecks 10,000 miles around the world for 3 years in search of the most important person in the world to him. But as he learns the factual truths behind his lost fiance, he also finds out the shocking facts behind his own survival.

Collects Y- The Last Man #1-60