Prison escapee Luther Hecks (Duane Whitaker), with Texas Ranger Otis Lawson (Bo Hopkins) on his tail, co-opts his former cell mate Buck (Robert Patrick) to round up the old gang - C.W. Niles (Muse Watson), Jesus (Raymond Cruz), and Ray Bob (Brett Harrelson) and meet him at the El Coyote Motel in Mexico. On the way in his car, Luther hits and kills a big bat. Unbeknown to Luther the bat is actually a vampire Victor (Joe Virzi). At a nearby bar, the Titty Twister (open from dusk till dawn) he is subdued by Victor and fellow vampire, bartender Razor Eddie (Danny Trejo) and turned into a vampire. At the El Coyote, Buck, Roy Bob, C.W., and Jesus are watching porno movies when Luther arrives and attacks Jesus' lady-of-the-evening, turning her into a vampire. She then turns Jesus. The gang head off to Bravos to rob the bank. Once inside, Luther and Jesus bite the guard and start working on the other boys. When Ranger Otis and a huge SWAT team arrive and surround the bank, the blood bath really starts in a desperate fight to the finish between he cops and the bank-robbing gang of vicious bloodsuckers in this bloody action-packed, terror-fest worthy of the mighty duo of Tarantino and Rodriguez.