Both Alice (Alba Rorwacher) and Mattia (Luca Marinelli) are fated by childhood accidents to live as outsiders. Fiercely intelligent, they match up together on some levels, but not at all on others they are the prime numbers of the title. This incredible film adapted from the best-selling novels turns their lives into full speed melodrama with superb soundtrack (Mike Patton) and great support cast (inc Isabella Rossellini). Its as exciting as new Italian cinema gets, sweeping in its arc, devastating in its conclusion. See why this film has been so awarded since release.