DCs strangest group of heroes: Cliff Steele aka Robotman (Brendan Fraser), Larry Trainor aka Negative Man (Matt Bomer), Rita Farr aka Elasti-Woman (April Bowlby), Crazy Jane (Diane Guerrero), and Victor Stone aka Cyborg (Joivan Wade) are back again to save the world that is if they can find a way to grow up - both figuratively and literally. Following the defeat of Mr. Nobody, the Doom Patrol now find themselves mini-sized and stranded on Cliffs toy race car track. Here they begin to deal with their feelings of betrayal with Niles Caulder aka The Chief (Timothy Dalton), while confronting their own personal baggage. And as each member faces the challenge of growing beyond their own past traumatic experiences, they must come together to embrace and protect the newest member of the family, Dorothy (Abigail Shapiro), Caulder's daughter, whose powers remain a mysterious but real threat to bringing on the end of the world.