Mischief and her side-cat Mayhem are your respectably heinous villains. They'll spoil new movies, steal cake from parties they weren't invited to, and hit the good citizens where it'll dirty them most "their toilet paper. But before Mischief and Mayhem were ever supervillains, they were just Missy and Gizmo, fresh recruits at superhero boot camp. Except Missy lied on her hero application and has exactly zero superpowers, just her brainpower. Humiliated when caught and kicked out, she has only one fellow camp recruit who is willing to stand by her "Melvira. Unbeknownst to others, Melvira has her own villainous agenda, and it involves helping Missy cross the line into villainy as a new alter ego, Mischief.

Something about Melvira doesn't sit right with Missy, and soon she'll be called upon to battle her former best friend ... but will Missy be able to face the friend who was once her defender?