Forensic physician Dr Anya Crichton is presented with a patient who has returned from her honeymoon with multiple sexually transmitted infections. Her husband has none of them. She tearfully denies having had any other partners and Anya believes her. Is this a medical phenomenon or has something more sinister taken place? Anya’s investigations into the case leads to a ground breaking study that attracts international attention. Her expertise leads to an invitation to New York to address over three hundred football players in the USA Professional League. The enigmatic private investigator Ethan Rye is assigned to assist Anya during the summit and when an alleged rape involving five football players takes place, Anya is commissioned to investigate. She is immediately thrust into a subculture of violence, sexual assault and drug abuse. No one is what he or she seems.